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Year : 2016  |  Volume : 6  |  Issue : 2  |  Page : 45-50

Level of total and specific fungus IgE in allergic fungal sinusitis: how it affects management and follow-up

Department of Otorhinolaryngology, Kasr El Aini College of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Ahmed Kamel
Department of Otorhinolaryngology, Kasr El Aini College of Medicine, Cairo University, 20 Ibrahim Nagy Street 10th district, Nasr City, Cairo
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2090-7540.200617

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Objective The aim of this study was to evaluate the relationship between the level of total serum IgE and the prognosis of allergic fungal sinusitis, possibility of recurrence and level of aggressiveness. Type of the study This study was a prospective controlled one. Patients and methods Forty patients who were diagnosed as having allergic fungal sinusitis were randomly divided into two equal groups. One group (group A) received postoperative systemic steroids, whereas the other group (group B) received postoperative local steroids only. The patients were followed up for 6 months with endoscopy and IgE level evaluation. Results The total number of patients who had recurrence of the disease 6 months postoperatively was 17. Six of them were from group A (systemic steroids) and 11 were from group B (local steroids only). Conclusion Allergic fungal sinusitis should be treated with minimal surgical or endoscopic procedures, followed by local and more important systemic steroids for a prolonged period. Patients should be followed up at close intervals postoperatively using nasal endoscopy and more importantly serum IgE (total and if available fungus specific) as it is a good indicator to the future possibility of recurrence and thus the possibility of resurgery or further medical treatment.

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